Molecular cytogenetics refers to the study of chromosomal structures with use of molecular techniques. The technique provides a combination of both molecular and cytological approach to research and diagnosis. Molecular cytogenetics is being considered as an indispensable tool for the diagnosis and research of numerous chromosomal aberrations. The technique is preferred over traditional chromosomal banding technique as traditional techniques provide low resolution level and may escape detection of copy number variations.
The breakthrough in the molecular cytogenetics technologies such FISH and aCGH are providing new dimensions to the areas of research and molecular diagnostics. These techniques are considered as invaluable tool for gene mapping, gene discovery and complex disease trait analysis. Molecular cytogenetics facilitates diagnosis and prognosis of diseases associated with hematological malignancies and solid tumors at molecular level. Likewise, alongwith diagnosis and prognosis of tumors, the technique is facilitating the practice of personalized medicines. The global molecular cytogenetics market was valued at USD 469.2 million in 2012 and is expected to grow at a CAGR of 23.4% from 2013 to 2019 to reach at an estimated value of USD 1.9 billion in 2019.
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Overview of the molecular cytogenetics market
The global molecular cytogenetics market, expected to grow at 23.4% CAGR from 2013-2019, has provided a breakthrough in the fields of research and molecular diagnostics. Earlier restricted to merely identifying chromosome structure, the area of cytogenetics has expanded to assessing structural and functional genetic anomalies. The aCGH technique is currently growing at a CAGR of over 20% compared to FISH technique and is predicted to dominate the market in the forecast period. The main reasons for its rising demand are high resolution, accurate analysis, rapid results and the ability to perform thousands of experiments in a single array, hence saving time and cost.
The market for molecular cytogenetics is driven by numerous forces such as rising cases of cancer across the world, increased level of public awareness, mounting popularity of personalized medicines, growing per capita spending capacity, higher R&D activities and laboratories, and use of advanced technology in molecular cytogenetics. Region-wise, North America dominates the global market, followed by Europe. Countries in Asia-Pacific have emerged as potential markets owing to factors such as increasing population and the culture of consanguineous marriage which raises the risk of genetic disorders.
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